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Module 4: Medications - Advanced Knowledge
Airway anatomy

nerves or their branches can selectively be blocked for an awake bronchoscopic intubation:
- Trigeminal nerve (CN V) (nasal cavity, mouth)
                        
The nasal cavity is entirely innervated by the trigeminal nerve.
- Anterior ethmoidal nerve (from V1) – septum
 - Greater and lesser palatine nerves, from sphenopalatine ganglion in pterygopalatine fossa (V2)
 - Nasopalatine nerve, from sphenopalatine ganglion (V2) – septum
 
 - Glossopharyngeal nerve (CN IX) (posterior 1/3 tongue, pharynx, valleculae, lingual surface of epiglottis and gag reflex)
                        
Gag reflex:
- Elicited by stimulation of the glossopharyngeal nerve, efferent from vagus nerve
 - Abolished by bilateral block of glossopharyngeal nerve
 
 - Vagus nerve (X) (larynx, trachea)
                         
The superior laryngeal nerve divides into internal and external branches.
- Internal branch: sensation from epiglottis to above vocal cords
 - External branch: cricothyroid muscle
 
Recurrent laryngeal nerve:
- Given off the vagus nerve during it's intra-thoracic course (loops around ligamentum arteriosum on left and around subclavian artery on right)
 - Provides sensation of larynx below and including vocal cords and trachea. Motor to all intrinsic muscles of the larynx except cricothyroid muscle
 - Glottic closure reflex (exaggeration of this reflex = laryngospasm) – this is caused by stimulation of superior laryngeal nerve, efferent from recurrent laryngeal nerve
 
 
Nerve blocks
Superior laryngeal nerve (sensation to larynx above vocal cords)
- Blocked between hyoid bone and thyroid cartilage where it penetrates the thyrohyoid membrane
 - Place patient supine with maximal neck extension
 - Grab the hyoid between the thumb and index finger and firmly displace it towards the side to be blocked
 - Advance a 25g needle to the greater cornu then walk it off inferiorly and advance it a further 2 – 3mm
 - Inject 2 – 3ml and an additional 1ml as the needle is withdrawn (to block the external branch)
 
Glossopharyngeal nerve: (gag reflex and sensation from the oropharynx to the lingual surface of the epiglottis)
- Usually blocked by the local anesthetic applied to the back of the tongue and throat
 - Can also be blocked by holding a local anesthetic soaked swab bilaterally at the palato-glossal arch (the rim of tissue than runs from the uvula to the base of the tongue)
 
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The glossopharyngeal nerve can be blocked by holding swabs soaked in local anesthetic at the point indicated by the white arrow.
Continue to: Module 5: Procedure